Technology & Services

Germ-Free Experimental Services

Germ-Free Rederivation Services

SPF Rederivation Services

IVF Services

CRO Services

Germ-Free Experimental Services

MQM Microbiological Research Institute operates nearly 1,000 square meters of high-standard germ-free animal facilities, equipped with imported next-generation flexible film isolators for germ-free animal housing. These isolators offer extended durability and significantly reduced risk of rupture or contamination. Supported by a highly trained, specialized germ-free mouse team, Mingqian has established a strict and standardized operating system for germ-free husbandry and experimentation.

We are committed to providing high-quality germ-free mouse models and technical services for universities, research institutes, and biopharmaceutical enterprises across China.

Global Standards, Internationally Aligned Platform

Germ-free mouse management is technically demanding—any deviation in procedure can lead to microbial contamination. Mingqian strictly adheres to internationally recognized SOPs, maintaining standards equivalent to those of leading institutions in the US and Europe across materials management, colony breeding, and microbiological monitoring.

1. Material Control

A rigorous disinfection and entry-exit protocol is enforced to significantly reduce the risk of contamination during animal husbandry.

2. Colony Management

• Foundation & Expansion Colonies: Managed through sibling mating to preserve genetic consistency.

• Production Colonies: Managed via random mating to support broader experimental needs.

3. Microbiological Monitoring

• Weekly: Aerobic and anaerobic microbial testing on animal and environmental samples inside isolators.

• Quarterly: Live germ-free mice undergo comprehensive microbial screening covering 57 pathogens, including viruses, bacteria, and parasites.

• Real-Time Monitoring: Environmental audits help identify contamination risks in isolators at an early stage.

Germ-Free Mouse Services

MQM offers a full suite of services across the germ-free mouse research ecosystem:

• Sales and nationwide delivery of standard germ-free mouse strains

• Contract research services using germ-free platforms, including microbiota transplantation and disease model construction

• SPF-to-germ-free purification services for SPF-grade mice

• Custom germ-free processing for gene-edited mouse strains

• CBC isolator sales, germ-free platform construction support, and on-site technical training

MQM is dedicated to empowering microbiome research with industry-leading infrastructure, standardized systems, and professional service delivery. Contact us to learn how we can support your germ-free research needs.