So many animals, why must choose mice as experimental animals?
2023-11-15
Mice are the most common subjects in all scientific and medical experiments. The toxic (LD50) values of all poisonous snakes we see are all data obtained by subcutaneous injection or intraperitoneal injection of mice. So, have you ever wondered why you choose mice as experimental animals instead of other animals? Today we will talk about this interesting question.
First of all, let's briefly understand the mice.
The mouse is not a single name of some kind of mouse,A general term for all experimental rodents,Which mainly includes two kinds: Experimental mice of the albino strain and experimental rats of the albino strain.
The experimental mouse is the product of the domestication of the mouse, specifically the Western European mouse or the offspring of the domestication of the Eastern European mouse. According to the existing records, as early as the 17th century, British biologist Robert Hooke was the first person to use mice as experimental animals. After that, for a long time, scientists all over the world directly chose mice as experimental animals.
It wasn't until 1909 that Harvard geneticist Clarence Cook Little used inbreeding to develop the first strain of experimental mice-Mouse inbred strain DBA/2.
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